p41-ARCb Polyclonal Antibody, Invitrogen™

Goat Polyclonal Antibody

Brand:  Invitrogen PA518047

Product Code. 11386013

Description

This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.

Specifications

• Antigen: p41-ARCb
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ARPC1B
• Gene Alias: 41kDa; AA408064; AA408534; AA571392; actin related protein 2/3 complex subunit 1B; actin related protein 2/3 complex subunit 1B, 41kDa; actin related protein 2/3 complex, subunit 1B; actin related protein 2/3 complex, subunit 1B, 41kDa; actin-related protein 2/3 complex subunit 1B; Actin-related protein complex 1b; AF007010; ARC41; Arp2/3 complex 41 kDa subunit; ARP2/3 protein complex subunit p41; Arpc1b; AW208418; L72; OTTHUMP00000206020; p40-ARC; p41-ARC; SOP2Hs
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 10095
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O15143
• Gene Symbols: ARPC1B
• Immunogen: Synthetic peptide sequence (AYHSFLVEPISCH) corresponding to the N-terminus amino acids of ARPC1B
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG