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AKR1B10 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA522036
Code : LD
Additional Details : Weight : 0.01000kg
Description
Recommended positive controls: Molt-4, Raji, mouse colon, rat colon, Jurkat, NCI-H929. Predicted reactivity: Mouse (82%), Rat (82%), Rabbit (86%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
AKR1B10, a 316aa protein, catalyzes efficient reduction ofaliphatic and aromatic aldehydes. It the first cytosolic NADP (H)-dependent retinal reductase described in humans and is characterized by the presence of a novel NADP binding motif. Due to its ability to convert glucose to sorbitol, AKR1B10 may have a role in development of secondary diabetic complications.It is abundantly expressed in adrenal gland, small intestine and colon, with lower levels in liver, thymus, prostate, testis, and skeletal muscle and its levels are up regulated in certain cancers such as hepatocellular carcinoma.Specifications
AKR1B10 | |
Polyclonal | |
Unconjugated | |
Akr1b10 | |
2310005E10Rik; AKR1B10; AKR1B11; AKR1B12; Akr1b16; aldo-keto reductase family 1 member B10; aldo-keto reductase family 1, member B10; aldo-keto reductase family 1, member B10 (aldose reductase); aldo-keto reductase family 1, member B11 (aldose reductase-like); Aldose reductase-like; aldose reductase-like 1; aldose reductase-like peptide; aldose reductase-related protein; ALDRLn; ARL1; ARL-1; ARP; hARP; HIS; HSI; MGC14103; SI reductase; small intestine reductase | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
296972, 57016, 67861 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
O60218 | |
Akr1b10 | |
Full length human AKR1B10 Recombinant protein. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |