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AKAP4 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA554129
Additional Details : Weight : 0.02000kg
Description
Immunogen sequence: EIIVIKDTEK KDQSKTEGSV CLFKQAPSDP VSVLNWLLSD LQKYALGFQH ALSPSTSTCK HKVGDTEGEY HRASSENCYS VYADQVNIDY LMNRPQNLRL EMTAAKNTNN NQSPSAPPAK PPSTQRAVIS PDGECSIDD Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 82%.
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP4, also known as hAKAP82, is a major sperm fibrous sheath protein that localizes to the entire length of the flagellum of human sperm. It has been suggested that AKAP4 plays multiple roles in sperm motility and regulation of signal transduction pathways. AKAP4 has also been postulated to be a potential biomarker for breast cancer.Specifications
AKAP4 | |
Polyclonal | |
Unconjugated | |
AKAP4 | |
75 kDa fibrous sheath protein; A kinase (PRKA) anchor protein 4; AKAP 82; AKAP4; AKAP-4; akap4 {ECO:0000312; AKAP82; A-kinase anchor protein 4; A-kinase anchor protein 82 kDa; A-kinase anchoring protein 4; cancer/testis antigen 99; CT99; Fsc1; hAKAP82; HI; major sperm fibrous sheath protein; mAKAP82; p82; PRKA4; protein kinase A anchoring protein 4; protein kinase A-anchoring protein 4; RGD:620828}; testis-specific gene HI | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
8852 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry | |
0.2 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q5JQC9 | |
AKAP4 | |
Recombinant protein corresponding to Human AKAP4 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Research Use Only