4-Nitrophenol, 99%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11466967	Thermo Scientific Alfa Aesar A14376.30	250 g
11456967	Thermo Scientific Alfa Aesar A14376.0B	1000 g
11476967	Thermo Scientific Alfa Aesar A14376.0I	5000 g

Description

4-Nitrophenol is used as a precursor to prepare phenetidine, acetophenetidne and pH indicator. Its carboxylate ester derivatives are involved as an active component for the construction of amide moieties in peptide synthesis. It is used as an intermediate in the synthesis of paracetamol and N-acetyl-p-aminophenol dyestuffs.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Nitrophenol is used as a precursor to prepare phenetidine, acetophenetidne and pH indicator. Its carboxylate ester derivatives are involved as an active component for the construction of amide moieties in peptide synthesis. It is used as an intermediate in the synthesis of paracetamol and N-acetyl-p-aminophenol dyestuffs.

Solubility
Freely soluble in alcohol, chloroform, ether. Freely soluble in acetone. Slightly soluble in water.

Notes
Incompatible with strong oxidizing agents and strong bases.

Chemical Identifiers

• CAS: 100-02-7
• Molecular Weight (g/mol): 139.11
• InChI Key: BTJIUGUIPKRLHP-UHFFFAOYSA-N
• PubChem CID: 980
• IUPAC Name: 4-nitrophenol

• Molecular Formula: C6H5NO3
• MDL Number: MFCD00007331
• Synonym: p-nitrophenol, phenol, 4-nitro, paranitrophenol, niphen, 4-hydroxynitrobenzene, p-hydroxynitrobenzene, phenol, p-nitro, mononitrophenol, paranitrofenol, paranitrofenolo
• ChEBI: CHEBI:16836
• SMILES: OC1=CC=C(C=C1)[N+]([O-])=O

Specifications

• CAS: 100-02-7
• Density: 1.48
• Flash Point: 169°C (336°F)
• MDL Number: MFCD00007331
• Beilstein: 1281877
• Merck Index: 14,6621
• Solubility Information: Freely soluble in alcohol,chloroform,ether; Freely soluble in acetone; Slightly soluble in water.
• SMILES: OC1=CC=C(C=C1)[N+]([O-])=O
• Molecular Weight (g/mol): 139.11
• ChEBI: CHEBI:16836
• Percent Purity: 99%

• Melting Point: 110°C to 115°C
• Boiling Point: 279°C (decomposition)
• Molecular Formula: C6H5NO3
• UN Number: UN1663
• Sensitivity: Light sensitive
• Synonym: p-nitrophenol, phenol, 4-nitro, paranitrophenol, niphen, 4-hydroxynitrobenzene, p-hydroxynitrobenzene, phenol, p-nitro, mononitrophenol, paranitrofenol, paranitrofenolo
• InChI Key: BTJIUGUIPKRLHP-UHFFFAOYSA-N
• IUPAC Name: 4-nitrophenol
• PubChem CID: 980
• Formula Weight: 139.11
• Chemical Name or Material: 4-Nitrophenol

Safety and Handling

GHS H Statement
H373-H302-H312-H332
May cause damage to organs through prolonged or repeated exposure.
Harmful if swallowed.
Harmful in contact with skin.
Harmful if inhaled.

P260-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P312-P314-P330-P363-P501c

H301-H312+H332-H373-H500

missing translation for 'dotInformation' : Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: NITROPHENOLS

missing translation for 'einecsNumber' : 202-811-7

missing translation for 'rtecsNumber' : SM2275000

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

Product Identifier

• 4-Nitrophenol

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3
• Acute toxicity Category 4
• Specific target organ toxicity after repeated exposure Category 2

Hazard Statement

• H301-Toxic if swallowed.
• H312-Harmful in contact with skin.
• H332-Harmful if inhaled.
• H373-May cause damage to organs.

Precautionary Statement

• P260-Do not breathe dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.

Supplemental information

• MIXTURE LIST-Contains : p-Nitrophenol

RUO – Research Use Only