4'-Hydroxy-3'-methoxyacetophenone, 98%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11448653	Thermo Scientific Alfa Aesar A10439.18	50 g
11458653	Thermo Scientific Alfa Aesar A10439.30	250 g
11344719	Thermo Scientific Alfa Aesar A10439.36	500 g

Description

4'-Hydroxy-3'-methoxyacetophenone is used as an inhibitor of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, which is an enzyme responsible for reactive oxygen species production. It is also useful in the treatment of various inflammatory diseases and atherosclerosis. Further, it shows an anti-inflammatory activity and improves endothelial function by reducing oxidative stress. In addition to this, it is used for studying nitric oxide regulated processes in plants.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in ethanol, chloroform, ether, hot water, benzene, ethyl acetate and dimethyl sulfoxide. Insoluble in petroleum ether.

Notes
Incompatible with strong oxidizing agents.

Chemical Identifiers

• CAS: 498-02-2
• Molecular Weight (g/mol): 166.18
• InChI Key: DFYRUELUNQRZTB-UHFFFAOYSA-N
• PubChem CID: 2214
• IUPAC Name: 1-(4-hydroxy-3-methoxyphenyl)ethanone

• Molecular Formula: C9H10O3
• MDL Number: MFCD00008747
• Synonym: acetovanillone, apocynin, 4'-hydroxy-3'-methoxyacetophenone, 1-4-hydroxy-3-methoxyphenyl ethanone, acetoguaiacone, acetoguaiacon, apocynine, 4-acetyl-2-methoxyphenol, acetovanilone, acetovanyllon
• ChEBI: CHEBI:2781
• SMILES: COC1=CC(=CC=C1O)C(C)=O

Specifications

• CAS: 498-02-2
• Boiling Point: 295°C to 300°C
• MDL Number: MFCD00008747
• Merck Index: 14,741
• Solubility Information: Soluble in ethanol,chloroform,ether,hot water,benzene,ethyl acetate and dimethyl sulfoxide. Insoluble in petroleum ether.
• SMILES: COC1=CC(=CC=C1O)C(C)=O
• Molecular Weight (g/mol): 166.18
• ChEBI: CHEBI:2781
• Percent Purity: 98%

• Melting Point: 112°C to 116°C
• Molecular Formula: C9H10O3
• Beilstein: 637373
• Synonym: acetovanillone, apocynin, 4'-hydroxy-3'-methoxyacetophenone, 1-4-hydroxy-3-methoxyphenyl ethanone, acetoguaiacone, acetoguaiacon, apocynine, 4-acetyl-2-methoxyphenol, acetovanilone, acetovanyllon
• InChI Key: DFYRUELUNQRZTB-UHFFFAOYSA-N
• IUPAC Name: 1-(4-hydroxy-3-methoxyphenyl)ethanone
• PubChem CID: 2214
• Formula Weight: 166.18
• Chemical Name or Material: 4'-Hydroxy-3'-methoxyacetophenone

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

H315-H319-H335

missing translation for 'einecsNumber' : 207-854-5

missing translation for 'rtecsNumber' : AM8800000

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

RUO – Research Use Only