4-Acetylpyridine, 98%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11469862	Thermo Scientific Alfa Aesar A12015.14	25 g
11479862	Thermo Scientific Alfa Aesar A12015.22	100 g
11489862	Thermo Scientific Alfa Aesar A12015.36	500 g

Description

4-acetylpyridine on reaction with - and 4-formylpyridine (H3FoPyS, H4FoPyS) yields semicarbazones. Reaction of acetylpyridine with thiophene-2-carboxaldehyde afforded the 2-chloro-6-ethoxy-4-β-(2-thienyl)acryloylpyridine, which was reacted with malononitrile in refluxing ethanol in the presence of piperidine as a catalyst to afford the cyanoaminopyrane derivative.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-acetylpyridine on reaction with - and 4-formylpyridine (H3FoPyS, H4FoPyS) yields semicarbazones. Reaction of acetylpyridine with thiophene-2-carboxaldehyde afforded the 2-chloro-6-ethoxy-4-β-(2-thienyl)acryloylpyridine, which was reacted with malononitrile in refluxing ethanol in the presence of piperidine as a catalyst to afford the cyanoaminopyrane derivative.

Solubility
Insoluble in water. Soluble in alcohol.

Notes
Store in cool place. Keep away from oxidizing agents.

Chemical Identifiers

• CAS: 1122-54-9
• Molecular Weight (g/mol): 121.139
• InChI Key: WMQUKDQWMMOHSA-UHFFFAOYSA-N
• PubChem CID: 14282
• SMILES: CC(=O)C1=CC=NC=C1

• Molecular Formula: C7H7NO
• MDL Number: MFCD00006433
• Synonym: 4-acetylpyridine, methyl 4-pyridyl ketone, ethanone, 1-4-pyridinyl, ketone, methyl 4-pyridyl, 1-pyridin-4-yl ethan-1-one, 1-pyridin-4-yl ethanone, pyridine, 4-acetyl, 4-acetyl pyridine, 4-pyridyl methyl ketone, unii-g47437iow7
• IUPAC Name: 1-pyridin-4-ylethanone

Specifications

• CAS: 1122-54-9
• Density: 1.103
• Flash Point: 104°C (219°F)
• Refractive Index: 1.535
• Beilstein: 107629
• Solubility Information: Insoluble in water. Soluble in alcohol.
• SMILES: CC(=O)C1=CC=NC=C1
• Molecular Weight (g/mol): 121.139
• Formula Weight: 121.14
• Chemical Name or Material: 4-Acetylpyridine

• Melting Point: 14°C to 16°C
• Boiling Point: 210°C to 212°C
• Molecular Formula: C7H7NO
• MDL Number: MFCD00006433
• Synonym: 4-acetylpyridine, methyl 4-pyridyl ketone, ethanone, 1-4-pyridinyl, ketone, methyl 4-pyridyl, 1-pyridin-4-yl ethan-1-one, 1-pyridin-4-yl ethanone, pyridine, 4-acetyl, 4-acetyl pyridine, 4-pyridyl methyl ketone, unii-g47437iow7
• InChI Key: WMQUKDQWMMOHSA-UHFFFAOYSA-N
• IUPAC Name: 1-pyridin-4-ylethanone
• PubChem CID: 14282
• Percent Purity: 98%

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

H315-H319-H335

missing translation for 'einecsNumber' : 214-350-9

missing translation for 'rtecsNumber' : OB5426000

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

RUO – Research Use Only