1-Methoxy-3-trimethylsiloxy-1,3-butadiene, 96%, Thermo Scientific Chemicals

Description

1-Methoxy-3-trimethylsiloxy-1,3-butadiene is employed as a reagent in Mannich-Michael reaction for the synthesis of piperidinones and enaminones. As Diels-Alder diene, it is used in the synthesis of pyridones and pyranones, sulfone analogues of griseofulvin (sulfogriseofulvins) and 4H-1-aminopyrroles and 4, 5H-pyrazoles.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Methoxy-3-trimethylsiloxy-1,3-butadiene is employed as a reagent in Mannich-Michael reaction for the synthesis of piperidinones and enaminones. As Diels-Alder diene, it is used in the synthesis of pyridones and pyranones, sulfone analogues of griseofulvin (sulfogriseofulvins) and 4H-1-aminopyrroles and 4, 5H-pyrazoles.

Solubility
Miscible with most organic solvents. Immiscible with water.

Notes
Moisture sensitive. Store in cool place. Incompatible with strong oxidizing agents and strong acids.

Specifications

Chemical Identifiers

• CAS: 54125-02-9
• Molecular Formula: C8H16O2Si
• Molecular Weight (g/mol): 172.299
• MDL Number: MFCD00008498
• InChI Key: SHALBPKEGDBVKK-VOTSOKGWSA-N
• Synonym: danishefsky's diene, 1-methoxy-3-trimethylsiloxy-1,3-butadiene, unii-1zor63u51o, 1-methoxy-3-trimethylsiloxy butadiene, 1-methoxy-3-trimethylsilyloxy-1,3-butadiene, e-4-methoxybuta-1,3-dien-2-yl oxy trimethylsilane, e-4-methoxybuta-1,3-dien-2-yloxy trimethylsilane, 1-methoxy-3-trimethylsilyloxy butadiene, silane, 2e-3-methoxy-1-methylene-2-propenyl oxy trimethyl, e-1-methoxy-3-trimethylsilyloxy-1,3-butadiene
• PubChem CID: 5366448
• IUPAC Name: [(3E)-4-methoxybuta-1,3-dien-2-yl]oxy-trimethylsilane
• SMILES: COC=CC(=C)O[Si](C)(C)C

• Boiling Point: 68°C to 69°C (14mmHg)
• Quantity: 1 g
• UN Number: UN1993
• Beilstein: 1616761
• Flash Point: 45°C (113°F)
• Merck Index: 14,6001
• Solubility Information: Miscible with most organic solvents. Immiscible with water.
• Formula Weight: 172.3
• Percent Purity: 97%
• Refractive Index: 1.455
• Sensitivity: Air and moisture sensitive
• Density: 0.89
• Chemical Name or Material: 1-Methoxy-3-trimethylsiloxy-1,3-butadiene

RUO – Research Use Only