1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide, 97%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11446037	Thermo Scientific Alfa Aesar B25057.06	5 g
11456037	Thermo Scientific Alfa Aesar B25057.14	25 g
11466037	Thermo Scientific Alfa Aesar B25057.22	100 g

Description

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide is used as a carboxyl activating agent and activate phosphate groups in phospho mono and di esters. It is used in peptide synthesis, 3'-amino-3'-deoxyadenosine-5'-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide is used as a carboxyl activating agent and activate phosphate groups in phospho mono and di esters. It is used in peptide synthesis, 3′-amino-3′-deoxyadenosine-5′-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.

Solubility
Soluble in water.

Notes
Air sensitive. Incompatible with strong acids and strong oxidizing agents.

Chemical Identifiers

• CAS: 1892-57-5
• Molecular Weight (g/mol): 155.245
• InChI Key: LMDZBCPBFSXMTL-UHFFFAOYSA-N
• PubChem CID: 15908
• SMILES: CCN=C=NCCCN(C)C

• Molecular Formula: C8H17N3
• MDL Number: MFCD00044916
• Synonym: 1-3-dimethylaminopropyl-3-ethylcarbodiimide, edac, 1-ethyl-3-3-dimethylaminopropyl carbodiimide, n1-ethylimino methylene-n3,n3-dimethylpropane-1,3-diamine, unii-rj5ozg6i4a, edci, 1,3-propanediamine, n'-ethylcarbonimidoyl-n,n-dimethyl, n-3-dimethylaminopropyl-n'-ethylcarbodiimide, rj5ozg6i4a, ethyldimethylaminopropyl carbodiimide
• IUPAC Name: 3-(ethyliminomethylideneamino)-N,N-dimethylpropan-1-amine

Specifications

• CAS: 1892-57-5
• Boiling Point: 66°C to 68°C (1 mmHg)
• Molecular Formula: C8H17N3
• Refractive Index: 1.461
• UN Number: UN2735
• Sensitivity: Air and moisture sensitive
• Solubility Information: Soluble in water.
• SMILES: CCN=C=NCCCN(C)C
• Molecular Weight (g/mol): 155.245
• Formula Weight: 155.24
• Chemical Name or Material: 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide

• Density: 0.885
• Flash Point: >110°C (230°F)
• Linear Formula: CH₃CH₂N=C=N(CH₂)₃N(CH₃)₂
• MDL Number: MFCD00044916
• Beilstein: 507429
• Synonym: 1-3-dimethylaminopropyl-3-ethylcarbodiimide, edac, 1-ethyl-3-3-dimethylaminopropyl carbodiimide, n1-ethylimino methylene-n3,n3-dimethylpropane-1,3-diamine, unii-rj5ozg6i4a, edci, 1,3-propanediamine, n'-ethylcarbonimidoyl-n,n-dimethyl, n-3-dimethylaminopropyl-n'-ethylcarbodiimide, rj5ozg6i4a, ethyldimethylaminopropyl carbodiimide
• InChI Key: LMDZBCPBFSXMTL-UHFFFAOYSA-N
• IUPAC Name: 3-(ethyliminomethylideneamino)-N,N-dimethylpropan-1-amine
• PubChem CID: 15908
• Percent Purity: 97%

Safety and Handling

GHS H Statement
H314-H318
Causes severe skin burns and eye damage.
Causes serious eye damage.

P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

H314-H335

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missing translation for 'tsca' : Yes

Recommended Storage : Store at -20°C; Store under Argon

Product Identifier

• 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide

Signal Word

• Danger

Hazard Category

• Serious eye damage/eye irritation Category 1
• Skin corrosion/irritation Category 1 B

Hazard Statement

• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide

RUO – Research Use Only