1-(2-Aminoethyl)piperidine, 98%, Thermo Scientific Chemicals

Descrizione

1-(2-Aminoethyl)piperidine is used in modification of vinylbenzyl chloride/divinylbenzene gel copolymer bead and in the synthesis of linkage isomers trans-bis[1-(2-aminoethyl)piperidine]dinitronickel and trans-bis[1-(2-aminoethyl)-piperidine]dinitritonickel. It is also used as a reactant for synthesis of: analogs of anticancer agents, inhibitor of botulinum neurotoxin serotype A light chain, P. falciparum malaria, and Ebola filovirus, cannabinoid CB1 receptor antagonists, small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells, potent and selective 5-HT6 antagonists and N-mustards as anticancer agents. 1-(2-Aminoethyl)piperidine on [1+1] condensation reaction with 3-methoxy salicylaldehyde yields tridentate Schiff base ligand.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-(2-Aminoethyl)piperidine is used in modification of vinylbenzyl chloride/divinylbenzene gel copolymer bead and in the synthesis of linkage isomers trans-bis[1-(2-aminoethyl)piperidine]dinitronickel and trans-bis[1-(2-aminoethyl)-piperidine]dinitritonickel. It is also used as a reactant for synthesis of: analogs of anticancer agents, inhibitor of botulinum neurotoxin serotype A light chain, P. falciparum malaria, and Ebola filovirus, cannabinoid CB1 receptor antagonists, small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells, potent and selective 5-HT6 antagonists and N-mustards as anticancer agents. 1-(2-Aminoethyl)piperidine on [1+1] condensation reaction with 3-methoxy salicylaldehyde yields tridentate Schiff base ligand.

Solubility
Partly miscible in water.

Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents, acid chlorides and acid anhydrides. It is sensitive to air.

Specifica

Identificatori chimici

• CAS: 27578-60-5
• Formula molecolare: C7H16N2
• Molecular Weight (g/mol): 128.219
• Numero MDL: MFCD00006516
• InChI Key: CJNRGSHEMCMUOE-UHFFFAOYSA-N
• Sinonimo: n-2-aminoethyl piperidine, 1-2-aminoethyl piperidine, 2-piperidin-1-yl ethanamine, 2-piperidin-1-yl ethan-1-amine, 1-piperidineethanamine, 2-piperidinoethylamine, 2-1-piperidinyl ethanamine, 2-1-piperidinyl ethylamine, n-aminoethylpiperidine, 2-piperidino-1-ethanamine
• PubChem CID: 33944
• IUPAC Name: 2-piperidin-1-ylethanamine
• SMILES: C1CCN(CC1)CCN

• Materiale o nome chimico: 1-(2-Aminoethyl)piperidine
• Densità: 0.903
• Punti di ebollizione: 185°C to 186°C
• Punto d'infiammabilità: 57°C (134°F)
• Indice di rifrazione: 1.474
• Quantità: 5 g
• Numero UN: UN2733
• Beilstein: 103469
• Sensibilità: Air Sensitive
• Informazioni di solubilità: Partly miscible in water.
• Peso formulazione: 128.22
• Percent Purity: 98%

Sicurezza e movimentazione

Avvertenza

• Pericolo

Categoria di pericolo

• Lesione oculare grave/irritazione oculare Categoria 1
• Liquido infiammabile Categoria 3
• Corrosione/irritazione della pelle Categoria 1B

Indicazioni di pericolo

• H226-Liquido e vapori infiammabili.
• H314-Provoca gravi ustioni cutanee e gravi lesioni oculari.
• H318-Provoca gravi lesioni oculari.

Consigli di prudenza

• P210-Tenere lontano da fonti di calore, superfici riscaldate, scintille, fiamme e altre fonti di innesco. Vietato fumare.
• P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
• P301+P330+P331-IN CASO DI INGESTIONE: sciacquare la bocca. NON provocare il vomito.
• P303+P361+P353-IN CASO DI CONTATTO CON LA PELLE (o con i capelli): togliere immediatamente tutti gli indumenti contaminati. Sciacquare la pelle/fare una doccia.
• P305+P351+P338-IN CASO DI CONTATTO CON GLI OCCHI: sciacquare accuratamente per parecchi minuti. Togliere le eventuali lenti a contatto se è agevole farlo. Continuare a sciacquare.
• P310-Contattare immediatamente un CENTRO ANTIVELENI/un medico .

RUO – Research Use Only