Trifluoroacetic Acid
Trifluoroacetic Acid, Optima™ LC/MS Grade, Fisher Chemical
CAS: 76-05-1 Molecular Formula: C2HF3O2 Molecular Weight (g/mol): 114.023 MDL Number: 4169 InChI Key: DTQVDTLACAAQTR-UHFFFAOYSA-N Synonym: trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoracetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova PubChem CID: 6422 ChEBI: CHEBI:45892 IUPAC Name: 2,2,2-trifluoroacetic acid SMILES: C(=O)(C(F)(F)F)O
Trifluoroacetic acid, 99.5%, for biochemistry, ACROS Organics™
CAS: 76-05-1 Molecular Formula: C2HF3O2 Molecular Weight (g/mol): 114.023 MDL Number: MFCD00004169 InChI Key: DTQVDTLACAAQTR-UHFFFAOYSA-N Synonym: trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoracetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova PubChem CID: 6422 ChEBI: CHEBI:45892 IUPAC Name: 2,2,2-trifluoroacetic acid SMILES: C(=O)(C(F)(F)F)O
Honeywell Fluka™ Trifluoroacetic acid, Puriss. p.a., for HPLC, ≥99.0% (GC), Honeywell Fluka™
CAS: 76-05-1 Molecular Formula: C2HF3O2 Molecular Weight (g/mol): 114.023 MDL Number: MFCD00009230 InChI Key: DTQVDTLACAAQTR-UHFFFAOYSA-N Synonym: trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoracetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova PubChem CID: 6422 ChEBI: CHEBI:45892 IUPAC Name: 2,2,2-trifluoroacetic acid SMILES: C(=O)(C(F)(F)F)O
Honeywell Fluka™ Trifluoroacetic acid, Reagent Grade, 99%, Honeywell™
CAS: 76-05-1 Molecular Formula: C2HF3O2 Molecular Weight (g/mol): 114.023 MDL Number: MFCD00004169 InChI Key: DTQVDTLACAAQTR-UHFFFAOYSA-N Synonym: trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoracetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova PubChem CID: 6422 ChEBI: CHEBI:45892 IUPAC Name: 2,2,2-trifluoroacetic acid SMILES: C(=O)(C(F)(F)F)O
Alfa Aesar™ Trifluoroacetic acid, 99%
CAS: 76-05-1 Molecular Formula: C2HF3O2 Molecular Weight (g/mol): 114.023 MDL Number: MFCD00004169 InChI Key: DTQVDTLACAAQTR-UHFFFAOYSA-N Synonym: trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoracetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova PubChem CID: 6422 ChEBI: CHEBI:45892 IUPAC Name: 2,2,2-trifluoroacetic acid SMILES: C(=O)(C(F)(F)F)O
Trifluoroacetic Acid, BAKER ANALYZED™ Reagent, J.T.Baker™
CAS: 76-05-1 Molecular Formula: C2HF3O2 Molecular Weight (g/mol): 114.023 InChI Key: DTQVDTLACAAQTR-UHFFFAOYSA-N Synonym: trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoracetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova PubChem CID: 6422 ChEBI: CHEBI:45892 IUPAC Name: 2,2,2-trifluoroacetic acid SMILES: C(=O)(C(F)(F)F)O
Alfa Aesar™ Trifluoroacetic acid, biochemical grade, 99.5+%
CAS: 76-05-1 Molecular Formula: C2HF3O2 Molecular Weight (g/mol): 114.023 MDL Number: MFCD00004169 InChI Key: DTQVDTLACAAQTR-UHFFFAOYSA-N Synonym: trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoracetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova PubChem CID: 6422 ChEBI: CHEBI:45892 IUPAC Name: 2,2,2-trifluoroacetic acid SMILES: C(=O)(C(F)(F)F)O
Honeywell Fluka™ Trifluoroacetic Acid, LC-MS Ultra, Honeywell™ Fluka™
CAS: 76-05-1 Molecular Formula: C2HF3O2 Molecular Weight (g/mol): 114.023 MDL Number: MFCD00004169 InChI Key: DTQVDTLACAAQTR-UHFFFAOYSA-N Synonym: trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoracetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova PubChem CID: 6422 ChEBI: CHEBI:45892 IUPAC Name: 2,2,2-trifluoroacetic acid SMILES: C(=O)(C(F)(F)F)O
Trifluoroacetic Acid, HPLC Grade, J.T.Baker™
CAS: 76-05-1 Molecular Formula: C2HF3O2 Molecular Weight (g/mol): 114.023 InChI Key: DTQVDTLACAAQTR-UHFFFAOYSA-N Synonym: trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoracetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova PubChem CID: 6422 ChEBI: CHEBI:45892 IUPAC Name: 2,2,2-trifluoroacetic acid SMILES: C(=O)(C(F)(F)F)O
Trifluoroacetic Acid, 99%, Alfa Aesar™
CAS: 76-05-1 Molecular Formula: C2HF3O2 Molecular Weight (g/mol): 114.023 MDL Number: MFCD00004169 InChI Key: DTQVDTLACAAQTR-UHFFFAOYSA-N Synonym: trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoracetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova PubChem CID: 6422 ChEBI: CHEBI:45892 IUPAC Name: 2,2,2-trifluoroacetic acid SMILES: C(=O)(C(F)(F)F)O
Trifluoroacetic acid, 99.5+%, Alfa Aesar™
CAS: 76-05-1 Molecular Formula: C2HF3O2 Molecular Weight (g/mol): 114.023 MDL Number: MFCD00004169 InChI Key: DTQVDTLACAAQTR-UHFFFAOYSA-N Synonym: trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoracetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova PubChem CID: 6422 ChEBI: CHEBI:45892 IUPAC Name: 2,2,2-trifluoroacetic acid SMILES: C(=O)(C(F)(F)F)O
Honeywell Fluka™ Trifluoroacetic Acid, For protein sequencing, Honeywell Fluka™
CAS: 76-05-1 Molecular Formula: C2HF3O2 Molecular Weight (g/mol): 114.023 MDL Number: MFCD00004169 InChI Key: DTQVDTLACAAQTR-UHFFFAOYSA-N Synonym: trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoracetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova PubChem CID: 6422 ChEBI: CHEBI:45892 IUPAC Name: 2,2,2-trifluoroacetic acid SMILES: C(=O)(C(F)(F)F)O
Honeywell Fluka™ Trifluoroacetic acid, Eluent additive for LC-MS, Honeywell Fluka™
CAS: 76-05-1 Molecular Formula: C2HF3O2 Molecular Weight (g/mol): 114.023 MDL Number: MFCD00004169 InChI Key: DTQVDTLACAAQTR-UHFFFAOYSA-N Synonym: trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoracetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova PubChem CID: 6422 ChEBI: CHEBI:45892 IUPAC Name: 2,2,2-trifluoroacetic acid SMILES: C(=O)(C(F)(F)F)O
Trifluoroacetic acid, CF₃CO₂H, CAS 76-05-1, also known as TFA, perfluoroacetic acid, 2,2,2-Trifluoroacetic acid or 2,2,2-Trifluoroethanoic acid, the trifluorinated derivative of acetic acid, is a strong organic monocarboxylic acid. It is a fuming, colourless liquid, miscible with water, ether, acetone, ethanol, benzene, hexane and carbon tetrachloride, and has a pungent, vinegar-like odour. Physical data: boiling point 72-73°; density 1.49 g/cm³; melting point -15.4 °C.
Applications of TFA are numerous, and include:
- Widespread use as a reagent in organic chemistry thanks to non-oxidising properties
- As a precursor in the manufacture of a wide range of other organic fluorinated organics, including agrochemicals and pharmaceuticals
- As a solvent, especially in NMR spectroscopy
- As an ion-pairing reagent in HPLC, especially for the separation of peptides and small proteins
- In peptide sequencing, especially for removal of t-boc protective groupings
Trifluoroacetic acid is corrosive to skin and eyes, harmful if inhaled and toxic to aquatic organisms if released to the environment. Storage in a cool, secure location is recommended.
This product is available in a wide range of grades and pack quantities to suit your application, for example:
- Extra pure
- LC/MS, HPLC and HPLC gradient
- Speciality grades for molecular biology and protein sequencing work
When using this product, the information and advice given in the Safety Data Sheet should be observed. Due attention should also be given to the appropriate precautions necessary for handling chemicals.
