Tris(3,6-dioxaheptyl)amine, 95%, Thermo Scientific Chemicals

Description

Tris(3,6-dioxaheptyl)amine acts as a phase transfer catalyst used in the preparation of 1,3-dideaza-2'-deoxyadenosine and related benzimidazole 2'-deoxyribonucleosides. It is also used as an intermediate in the synthesis of telithromycin. Further, it is used in the oxidation of arylmethanols under phase-transfer conditions. In addition to this, it acts as a cryptand during phase-transfer glycosylation of 2-amino-4-methoxy-7H-pyrrolo[2,3-d]pyrimidine.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Tris(3,6-dioxaheptyl)amine acts as a phase transfer catalyst used in the preparation of 1,3-dideaza-2′-deoxyadenosine and related benzimidazole 2′-deoxyribonucleosides. It is also used as an intermediate in the synthesis of telithromycin. Further, it is used in the oxidation of arylmethanols under phase-transfer conditions. In addition to this, it acts as a cryptand during phase-transfer glycosylation of 2-amino-4-methoxy-7H-pyrrolo[2,3-d]pyrimidine.

Solubility
Miscible with water.

Notes
Air sensitive and hygroscopic. Incompatible strong oxidizing agents and strong acids.

Specifications

Chemical Identifiers

• CAS: 70384-51-9
• Molecular Formula: C15H33NO6
• Molecular Weight (g/mol): 323.43
• MDL Number: MFCD00010748
• InChI Key: XGLVDUUYFKXKPL-UHFFFAOYSA-N
• Synonym: tris 2-2-methoxyethoxy ethyl amine, tris dioxa-3,6-heptyl amine, tris 3,6-dioxaheptyl amine, tda-1, 2-2-methoxyethoxy-n,n-bis 2-2-methoxyethoxy ethyl ethanamine, ethanamine, 2-2-methoxyethoxy-n,n-bis 2-2-methoxyethoxy ethyl, 8-2-2-methoxyethoxy ethyl-2,5,11,14-tetraoxa-8-azapentadecane, tris-2-2-methoxyethoxy ethyl amine
• PubChem CID: 112414
• IUPAC Name: 2-(2-methoxyethoxy)-N,N-bis[2-(2-methoxyethoxy)ethyl]ethanamine
• SMILES: COCCOCCN(CCOCCOC)CCOCCOC

• Melting Point: <-100°C
• Density: 1.011
• Boiling Point: 163°C to 171°C (1 mmHg)
• Flash Point: 162°C (323°F)
• Refractive Index: 1.4486
• Quantity: 25 g
• Beilstein: 2369296
• Sensitivity: Air sensitive; Hygroscopic
• Solubility Information: Miscible with water.
• Formula Weight: 323.43
• Percent Purity: 95%
• Chemical Name or Material: Tris(3,6-dioxaheptyl)amine

RUO – Research Use Only