Thermo Scientific Chemicals TRAM 34

Description

CAS: 289905-88-0 | C₂₂H₁₇ClN₂, C22H17ClN2 | 344.84 g/mol

TRAM-34 blocks intermediate conductance calcium-activated potassium channel IKCa1 with a Kd of 20nM and exhibits exquisite selectivity for the channel. Clotrimazole impurity. Also used to study its effect on the prevention of vascular restenosis after balloon angioplasty.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Specifications

• Quantity: 25 mg
• Description: Yellow
• Content And Storage: 2°C to 8°C
• For Use With (Application): TRAM-34 is a potent inhibitor of the intermediate-conductance calcium-activated potassium channel
• CAS: 289905-88-0
• Molecular Formula: C₂₂H₁₇ClN₂, C22H17ClN2
• Formula Weight: 344.84g/mol
• Synonym: 1-[(2-Chlorophenyl)diphenylmethyl]-1H-pyrazole
• Melting Point: 145°C to 147°C
• Solubility: Soluble in DMSO at 2mg/ml; Insoluble in water
• Product Type: Signal Transduction Reagent
• Form: Powder
• InChI Key: KBFUQFVFYYBHBT-UHFFFAOYSA-N
• SMILES: ClC1=CC=CC=C1C(N1C=CC=N1)(C1=CC=CC=C1)C1=CC=CC=C1
• IUPAC Name: 1-[(2-chlorophenyl)diphenylmethyl]-1H-pyrazole
• Molecular Weight (g/mol): 344.84

Safety and Handling

SDS

RUO – Research Use Only