tert-Butyl chloroacetate, 98%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11432518	Thermo Scientific Alfa Aesar A15833.14	25 g
11442518	Thermo Scientific Alfa Aesar A15833.22	100 g
11452518	Thermo Scientific Alfa Aesar A15833.36	500 g

Description

tert-Butyl chloroacetate is used in the synthesis of imidazol-1-yl-acetic acid hydrochloride, cis-disubstituted aziridine ester via aza-Darzens reaction and 1,10-diaza-18-crown-6 based sensors bearing a coumarin fluorophore.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
tert-Butyl chloroacetate is used in the synthesis of imidazol-1-yl-acetic acid hydrochloride, cis-disubstituted aziridine ester via aza-Darzens reaction and 1,10-diaza-18-crown-6 based sensors bearing a coumarin fluorophore.

Solubility
Decomposes in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Moisture sensitive. Incompatible with strong bases and strong oxidizing agents.

Chemical Identifiers

• CAS: 107-59-5
• Molecular Weight (g/mol): 150.602
• InChI Key: KUYMVWXKHQSIAS-UHFFFAOYSA-N
• PubChem CID: 66052
• SMILES: CC(C)(C)OC(=O)CCl

• Molecular Formula: C6H11ClO2
• MDL Number: MFCD00000930
• Synonym: tert-butyl chloroacetate, chloroacetic acid tert-butyl ester, acetic acid, chloro-, 1,1-dimethylethyl ester, t-butyl chloroacetate, tert-butylchloroacetate, acetic acid, chloro-, tert-butyl ester, chloroacetic acid t-butyl ester, acetic acid, 2-chloro-, 1,1-dimethylethyl ester, t-butylchloroacetate, t-butyl-chloroacetate
• IUPAC Name: tert-butyl 2-chloroacetate

Specifications

• CAS: 107-59-5
• Boiling Point: 155°C
• Odor: Ester-like
• Linear Formula: ClCH₂CO₂C(CH₃)₃
• MDL Number: MFCD00000930
• Beilstein: 1753006
• Synonym: tert-butyl chloroacetate, chloroacetic acid tert-butyl ester, acetic acid, chloro-, 1,1-dimethylethyl ester, t-butyl chloroacetate, tert-butylchloroacetate, acetic acid, chloro-, tert-butyl ester, chloroacetic acid t-butyl ester, acetic acid, 2-chloro-, 1,1-dimethylethyl ester, t-butylchloroacetate, t-butyl-chloroacetate
• InChI Key: KUYMVWXKHQSIAS-UHFFFAOYSA-N
• IUPAC Name: tert-butyl 2-chloroacetate
• PubChem CID: 66052
• Percent Purity: 98%

• Density: 1.053
• Flash Point: 46°C (115°F)
• Molecular Formula: C6H11ClO2
• Refractive Index: 1.423
• UN Number: UN2929
• Merck Index: 14,1563
• Solubility Information: Decomposes in water.
• SMILES: CC(C)(C)OC(=O)CCl
• Molecular Weight (g/mol): 150.602
• Formula Weight: 150.61
• Chemical Name or Material: tert-Butyl chloroacetate

Safety and Handling

GHS H Statement
H331-H226-H302-H312-H315-H319-H335
Toxic if inhaled.
Flammable liquid and vapour.
Harmful if swallowed.
Harmful in contact with skin.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P501c

H226-H302+H312-H314-H331-H335

missing translation for 'dotInformation' : Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: TOXIC LIQUIDS, FLAMMABLE, ORGANIC, N.O.S.

missing translation for 'einecsNumber' : 203-506-1

missing translation for 'rtecsNumber' : AF8985500

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3
• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 2
• Flammable liquid Category 3
• Skin corrosion/irritation Category 2

Hazard Statement

• H302-Harmful if swallowed.
• H312-Harmful in contact with skin.
• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H331-Toxic if inhaled.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P311-Call a POISON CENTER/doctor/ .

Show More

RUO – Research Use Only