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Thermo Scientific™ Silylation Grade Solvents
Use specially manufactured and packaged Thermo Scientific™ Silylation Grade Solvents to meet the exacting needs of silylation and other sensitive derivatization reactions.
Brand: Thermo Scientific™ TS-27530
Description
Use specially manufactured and packaged Thermo Scientific™ Silylation Grade Solvents to meet the exacting needs of silylation and other sensitive derivatization reactions. They are purified, dried, and packaged under nitrogen in convenient Thermo Scientific™ Hypo-Vial™ Sample Storage Vials, and are supplied with elastomer septa to enable immediate access to the sample without exposure to moisture and oxygen. Use polar solvents (acetonitrile, dimethylformamide, dimethylsulfoxide, pyridine, tetrahyrdrofuran) to facilitate reactions; nonpolar organic solvents may be used but will not accelerate the rate of reaction.
Recommended UseAvoid water or alcohol, as TMS reagents react with active hydrogen.
Avoid enolizable ketones.
Use dimethylformamide for steroids and other large molecules.
Use dimethylsulfoxide to prepare TMS derivatives of tertiary alcohols and some compounds with low solubility in other silylation solvents.
Pyridine is an excellent solvent and reaction medium for MS reactions and is an HCI acceptor in reactions involving organochlorosilanes.
Other commonly used solvents include tetrahydrofuran and acetonitrile.
Specifications
GC | |
Pyridine; 50 mL | |
98 to 100% |
Flammable, Harmful, Irritant | |
Pyridine | |
-20°C |
Safety and Handling
- Pyridine, Silyation Grade, 50 mL
Signal Word
- Danger
Hazard Category
- Acute toxicity Category 4
- Flammable liquid Category 2
Hazard Statement
- H225-Highly flammable liquid and vapour.
- H302-Harmful if swallowed.
- H332-Harmful if inhaled.
- H312-Harmful in contact with skin.
Precautionary Statement
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P264-Wash thoroughly after handling.
- P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
- P271-Use only outdoors or in a well-ventilated area.
- P370+P378-In case of fire: Use to extinguish.
- P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
- P302+P352-IF ON SKIN: Wash with plenty of water/.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
For Research Use Only. Not for use in diagnostic procedures.