PKM2 Mouse anti-Human, Mouse, Rat, Clone: 1C11C7, Proteintech

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
16847325	Proteintech 60268-1-IG-20UL	20 μL
16837325	Proteintech 60268-1-IG-150UL	150 μL

Description

PKM2, Pyruvate kinase isozymes M1/M2, has 2 isoforms. The immunogen of this antibody is M2 isoform, also called PKM2.

PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. PKM2 has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. PKM2 has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms of PKM2 have been reported.

Specifications

• Antigen: PKM2
• Concentration: 0.53 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: CTHBP, OIP 3, OIP3, Opa interacting protein 3, p58, PK2, PK3, PKM, PKM1, PKM2, PKM2 pyruvate kinase, muscle, Pyruvate kinase 2/3, Pyruvate kinase isozymes M1/M2, Pyruvate kinase muscle isozyme, TCB, THBP1, Tumor M2 PK
• Gene Symbols: PKM
• Isotype: IgG1
• Purification Method: Protein G
• Product Type: Antibody

• Clone: 1C11C7
• Applications: Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Immunofluorescence, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human, Rat, Mouse
• Gene Accession No.: P11980, P14618, P52480
• Gene ID (Entrez): 18746, 25630, 5315
• Immunogen: Peptide
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: PKM