Phospho-AKT (Ser473) Mouse anti-Human, Mouse, Clone: 1C10B8, Proteintech

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
16878325	Proteintech 66444-1-IG-20UL	20 μL
16868325	Proteintech 66444-1-IG-100UL	100 μL

Description

This antibody detects all the members of AKT with phospho-modification at Ser473.

The Akt family of serine/threonine protein kinases (also called protein kinase B/PKB) plays a key role in insulin signaling, cellular survival, and transformation. Akt1 is activated by phosphorylation on residues threonine 308 and Serine 473. Thr308, in the catalytic domain, is phosphorylated by the protein kinase PDK1, and Ser473, in the COOH-terminal regulatory domain, is phosphorylated by putative serine 473 kinase. To date, a couple of proteins have been shown to physically interact with PKB.

Specifications

• Antigen: Phospho-AKT (Ser473)
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: AKT, AKT1, AKT1-phospho-S473, pakt, p-AKT, Phospho akt, PKB, PKB ALPHA, PRKBA, Protein kinase B, Proto oncogene c Akt, RAC, RAC ALPHA, RAC PK alpha
• Gene Symbols: AKT1
• Isotype: IgG1
• Purification Method: Protein G
• Product Type: Antibody

• Clone: 1C10B8
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human, Mouse
• Gene Accession No.: P31749, P31750
• Gene ID (Entrez): 11651, 207
• Immunogen: Peptide
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: AKT1