Thermo Scientific Chemicals Oxaliplatin

Description

 

Oxaliplatin is an anti-tumor agent with activity against colorectal cancer. It shows antitumor activity in cell lines with acquired cisplatin resistance. It is used to treat cancer of the gullet (oesophagus). It is used as adjuvant therapy in patients who have had surgery to remove the cancer. It is used to treat testicular cancer.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Specifications

• Quantity: 50 mg
• Description: White to off-white
• Content And Storage: -30°C to -10°C
• CAS: 61825-94-3
• Molecular Formula: C8H14N2O4Pt
• Formula Weight: 397.29
• Synonym: NSC 266046;
• Solubility: Soluble in water with heating and/or sonication
• Product Type: Oxaliplatin
• Form: Crystalline solid
• MDL Number: MFCD00866327
• InChI Key: ZROHGHOFXNOHSO-WHMNLBETNA-L
• SMILES: O=C1O[Pt]OC1=O.N[C@@H]1CCCC[C@H]1N
• IUPAC Name: (1R,2R)-cyclohexane-1,2-diamine; 1,3-dioxa-2-platinacyclopentane-4,5-dione
• Molecular Weight (g/mol): 397.29

Safety and Handling

Signal Word

• Warning

Hazard Category

• Carcinogenicity Category 2
• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Skin sensitiser Category 1
• Specific target organ toxicity Category 3

Hazard Statement

• H315-Causes skin irritation.
• H317-May cause an allergic skin reaction.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.
• H351-Suspected of causing cancer.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P312-Call a POISON CENTER/doctor/if you feel unwell.

RUO – Research Use Only