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MEMO1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA566114
Additional Details : Weight : 0.01000kg
Description
Immunogen sequence: MSNRVVCREAS HAGSWYTASG PQLNAQLEGW LSQVQSTKRP ARAIIAPHAG YTYCGSCAAH AYKQVDPSIT RRI Highest antigen sequence identity to the following orthologs - mouse 99%, rat 73%.
May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.Specifications
MEMO1 | |
Polyclonal | |
Unconjugated | |
MEMO1 | |
0610016J10Rik; C21orf19-like protein; C2orf4; CGI-27; D930048L02Rik; fi04d12; HCV NS5A-transactivated protein 7; Hepatitis C virus NS5A-transactivated protein 7; hypothetical protein LOC327360; mediator of cell motility 1; Mediator of ErbB2-driven cell motility 1; MEMO; MEMO1; Memo-1; Methylation modifier for class I HLA; NS5ATP7; protein memo; protein MEMO1; RGD1309929; Unknown (protein for MGC:127714); wu:fi04d12; zgc:55290 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
51072, 7795 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunocytochemistry | |
0.05 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q9Y316 | |
MEMO1 | |
Recombinant Human MEMO1 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
For Research Use Only