Invitrogen™ Human LYN A, GST Tag Recombinant Protein

Human LYN A, GST Tag Recombinant Protein

Brand:  Invitrogen™ PV6448

Product Code. 15499053

Description

LYN is a protein-coding gene and is associated with diseases such as alexia and chorea-acanthocytosis. Activation of LYN has been shown to lead to imatinib resistance in CML patients. LYN B and the slightly shorter LYN A are the two isoforms of LYN. An important paralog of this gene is FRK. The full length LYN A protein enables researchers to study important mechanisms underlying disease.

• Increase disease relevance by interrogating a purified and active full-length LYN A reagent
• Uncover novel compounds or hits specific to the full length form
• Advance your research using the full-length protein and validated assays
• Assay Platforms: LanthaScreen™ TR-FRET Kinase Activity Assay, LanthaScreen™ Eu Kinase Binding Assay, and Z’-LYTE™ Kinase Activity Assay

Specifications

• Accession Number: NP_002341.1
• Molecular Weight (g/mol): 81 kDa
• Gene Alias: JTK8, FLJ26625
• Species: Human
• Protein Tag: GST Tag
• Expression System: Baculovirus
• Protein Form: Recombinant, Full Length
• Research Category: Signal Transduction

• For Use With (Application): Kinase Assay
• Quantity: 10μg
• KinaseFamily: SRC Kinase Family
• Recombinant: Recombinant
• Content And Storage: Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. If properly stored, this product is guaranteed for 6 months from date of purchase.
  
  Suspended in: 50 nM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.
• Protein Family: Kinases & Inhibitors
• Form: Liquid