Epredia™ Lab Vision™ Estrogen Receptor Ab-10 Mouse Monoclonal Antibody, 200μg/mL, biotinylated, BSA and azide

Ensure accurate, reproducible results in western blotting, immunoprecipitation, gel supershift and  chromatin precipitation experiments.

Brand:  Epredia™ MS-315-P0

Product Code. 12680967

Description

The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Mouse

Clone: TE111.5D11

Isotype: IgG1

Species Reactivity: Human, Cow, Pig, Dog, Mouse, Rat, Sheep, Rabbit, Hamster and Chicken. Others not known.

Epitope: aa 302-553

Immunogen: 35 kDa, C-terminal fragment (aa 302-595) of human ER expressed in E. coli

Molecular Weight: 67 kDa

Positive Control: T47D cells

Cellular Localization: Nuclear

Recommended for:

• Western Blotting
• Immunoprecipitation (Native and denatured)
• Gel Supershift
• Blocks Binding of Estrogen to ER
• Chromatin Precipitation

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Estrogen Receptor Ab-10
• Classification: Monoclonal
• Concentration: 200μg/mL
• Host Species: Mouse
• Quantity: 100 μL
• Research Discipline: Steroids Hormones and Growth Factors
• Target Species: Bovine, Canine, Chicken, Hamster, Human, Mouse, Porcine, Rabbit, Rat, Sheep
• Isotype: IgG1

• Applications: Immunoprecipitation
• Clone: TE111.5D11
• Conjugate: Unconjugated
• Immunogen: 35kDa, C-terminal fragment (aa 302-595) of human ER expressed in E. coli
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated