HSPA14 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Thermo Scientific PA561173

Product Code. 15748991

Description

Immunogen sequence: FTVLFPSGTP LPARRQHTLQ APGSISSVCL ELYESDGKNS AKEETKFAQV VLQDLDKKEN GLRDILAVLT MKRDGSLHVT CTDQETGKCE AIS Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 96%.

The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, the transportation of nascent poly-peptide chains across cellular membranes and the regulation of protein folding. HSPA14 (heat shock 70kDa protein 14), also known as HSP70-4 or HSP70L1, is a 509 amino acid novel HSP protein derived from human dendritic cells. Belonging to the heat shock protein 70 family, HSPA14 is thought to promote dendritic cell maturation. It is also suggested that HSPA14 stimulates secretion of the proinflammatory cytokines interleukin 12p70 (IL-12p70), IL-1 beta, TNF alpha, and the chemokines IP-10, MIP-1 alpha, MIP-1 beta and normal T cell expressed and secreted (RANTES).

Specifications

• Antigen: HSPA14
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HSPA14
• Gene Alias: 70kDa; heat shock 70 kDa protein 14; heat shock 70kDa protein 14; heat shock 70kDa protein 14 isoform 1 variant 3; Heat shock protein; heat shock protein 14; heat shock protein 4; heat shock protein family A (Hsp70) member 14; heat shock protein HSP60; heat shock protein hsp70-related protein; heat shock protein, 70 kDa 4; HSP; HSP60; Hsp70-4; HSP70L1; HSP70-like protein 1; HSP7E; HSPA14; hsr.1; NST-1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51182
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q0VDF9
• Gene Symbols: HSPA14
• Immunogen: Recombinant protein corresponding to Human HSPA14
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Research Use Only