Ephrin B1/B3 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA538067

Product Code. 15594991

Description

Eph receptors and ephrins exhibit complementary expression in many tissues during embryogenesis indicating that bidirectional activation of Eph receptors and ephrin-B proteins may occur at expression domain interfaces. Ephrin-B1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration. The distribution of ephrin-B1 in the developing retina suggests that it influences retinal axon mapping along the dorsal-ventral axis and may be involved in intratectal development The transmembrane ligand ephrin-B2 and its receptor tyrosine kinase EphB4 are specifically expressed on arterial and venous endothelial cells, respectively.

Specifications

• Antigen: Ephrin B1/B3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EFNB3
• Gene Alias: CEK5 ligand, CEK5 receptor ligand, CEK5-L, CEL5-L, EFL-3, EFNB1, ELK ligand, ELK-L, EPH-related receptor tyrosine kinase ligand 2, EPL2, EPLG2, Ephrin-B1 precursor, LERK-2, LERK2, STRA1, STRA1 protein, kinase ephrin-B1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13641, 13643, 1947, 1949, 25186, 360546
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P98172, Q15768, O35393, P52795, P52796
• Gene Symbols: EFNB1, EFNB3
• Immunogen: A synthetic non-phosphopeptide derived from human Ephrin B around the phosphorylation site of Tyr330 (N-I-Y-Y-K)
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG