EphB6 Monoclonal Antibody (8E7H12), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA515280

Product Code. 11385253

Description

MA5-15280 targets EphB6 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples. The MA5-15280 immunogen is purified recombinant fragment of EphB6 expressed in E. Coli.

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.

Specifications

• Antigen: EphB6
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Formulation: PBS with 0.03% sodium azide
• Gene Accession No.: O08644, O15197
• Gene Symbols: EPHB6
• Immunogen: Purified recombinant fragment of EphB6 expressed in E. Coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunohistochemistry, Western Blot
• Clone: 8E7H12
• Conjugate: Unconjugated
• Gene: EPHB6
• Gene Alias: Cekl; chicken eph/elk receptor-like protein; EPB6; EPH receptor B6; EPHB6; EphB6v; Epherin B6; Epherin receptor B6; ephrin type A receptor; ephrin type-B receptor 6; HEP; human kinase-defective Eph-family receptor protein; MEP; MGC129910; MGC129911; Tyrosine-protein kinase-defective receptor EPH-6
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 13848, 2051
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid