EphB4 Monoclonal Antibody (5B5), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA515506

Product Code. 11305483

Description

MA5-15506 targets EPHB4 in indirect ELISA, IF and WB applications and shows reactivity with Human samples. The MA5-15506 immunogen is purified recombinant extracellular fragment of human EPHB4 fused with hIgGFc tag expressed in HEK293 cell line.<br>. MA5-15506 detects EPHB4 which has a predicted molecular weight of approximately 108kDa.

EPHB4 is a receptor tyrosine kinase that belongs to the ephrin receptor family. Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by EphB4 binds to ephrin-B2 and plays an essential role in vascular development.

Specifications

• Antigen: EphB4
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.03% sodium azide
• Gene Accession No.: P54760
• Gene Symbols: EPHB4
• Immunogen: Purified recombinant extracellular fragment of human EPHB4 fused with hIgGFc tag expressed in HEK293 cell line.
• Regulatory Status: RUO
• Gene ID (Entrez): 2050
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunocytochemistry, Western Blot
• Clone: 5B5
• Conjugate: Unconjugated
• Gene: EPHB4
• Gene Alias: AI042935; Developmental kinase 2; EPH receptor B4; Ephb4; ephrin receptor EphB4; ephrin type-B receptor 4; Hepatoma transmembrane kinase; HTK; Mdk2; mDK-2; MYK1; soluble EPHB4 variant 1; soluble EPHB4 variant 2; soluble EPHB4 variant 3; TYRO11; Tyrosine kinase MYK-1; tyrosine-protein kinase receptor HTK; tyrosine-protein kinase TYRO11
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1