EPB41L2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA529485

Product Code. 13483627

Description

Recommended positive controls: 293T, H1299, HeLa, HepG2, Molt-4. Predicted reactivity: Mouse (87%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The 4.1 gene family encodes a group of multifunctional cytoskeletal proteins (4.1R, 4.1G, 4.1N and 4.1B), which are predominantly expressed in the nervous system. 4.1G is a protein that stabilizes spectrin-actin interactions and is associated with hereditary elliptocytosis. Red blood cell 4.1, designated 4.1R, is a multifunctional protein that is essential for maintaining erythrocyte shape and membrane mechanical properties. Both 4.1R and 4.1G are distributed in a unique pattern in the cerebellum and are believed to modulate the membrane mechanical properties of neuronal cells by promoting fodrin/actin association. 4.1N and 4.1B, designated EPB41L1 and EPB41L3, respectively, are strongly expressed in the brain. Antibodies to 4.1N have been reported to detect multiple forms, each enriched in postsynaptic density preparations relative to brain homogenate. Antibodies to 4.1B have been reported to detect two forms.

Specifications

• Antigen: EPB41L2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPB41L2
• Gene Alias: 4.1G; 4.1-G; AW555191; band 4.1-like protein 2; D10Ertd398e; DKFZp781D1972; DKFZp781H1755; Epb4.1l2; Epb41l2; erythrocyte membrane protein band 4.1 like 2; erythrocyte membrane protein band 4.1 like-protein 2; erythrocyte membrane protein band 4.1-like 2; erythrocyte membrane protein band 4.1-like 2 retinal; erythrocyte protein band 4.1 like 2; erythrocyte protein band 4.1l2 long; erythrocyte protein band 4.1l2 middle; erythrocyte protein band 4.1-like 2; generally expressed protein 4.1; NBL2; OTTHUMP00000040262; RGD1563977; RP3-324N14.1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2037
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.62 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O43491
• Gene Symbols: EPB41L2
• Immunogen: Recombinant fragment corresponding to a region within amino acids 107 and 384 of Human EPB41L2
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG