CDC42 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16826353	Proteintech 10155-1-AP-20UL	20 μL
16816353	Proteintech 10155-1-AP-150UL	150 μL

Description

This protein is a small GTPase of the Rho subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis, and cell progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42 1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrick syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in at least two transcript variants.

Specifications

• Antigen: CDC42
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunofluorescence, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Mouse, Rat, Human
• Gene Accession No.: P60766, P60953, Q8CFN2
• Gene ID (Entrez): 12540, 64465, 998
• Immunogen: CDC42 Fusion Protein Ag0207
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: CDC42

• Concentration: 0.35 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: CDC42, CDC42Hs, G25K, G25K GTP binding protein
• Gene Symbols: Cdc42
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody