Caffeine, 98.5%, specified according to the req. of USP/BP, Thermo Scientific Chemicals

Product Code	Brand	Quantity	Packaging
10254420	Thermo Scientific Acros 108160100	10 g	Glass Bottle
10264420	Thermo Scientific Acros 108165000	500 g	Plastic bottle
10744294	Thermo Scientific Acros 108160025	2.5 kg	Plastic bottle

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• Caffeine is an alkaloid vagal/vasomotor stimulant found in certain nuts, seeds, and legumes
• It is a methylxanthine, derived from a purine base compound found in the tissues of many organisms
• Caffeine competitively binds adenosine receptors and prevents signaling from dampening, thereby sustaining activation, and producing increases in energy

Chemical Identifiers

• CAS: 58-08-2
• Molecular Weight (g/mol): 194.19
• InChI Key: RYYVLZVUVIJVGH-UHFFFAOYSA-N
• PubChem CID: 2519
• IUPAC Name: 1,3,7-trimethylpurine-2,6-dione

• Molecular Formula: C8H10N4O2
• MDL Number: MFCD00005758
• Synonym: caffeine, 1,3,7-trimethylxanthine, guaranine, thein, cafeina, methyltheobromine, koffein, mateina, theine, alert-pep
• ChEBI: CHEBI:27732
• SMILES: CN1C=NC2=C1C(=O)N(C)C(=O)N2C

Specifications

• Acidity: 0.2mL of 0.01M NaOH max.
• Melting Point: 234.0°C to 239.0°C
• Density: 1.2300g/mL
• Infrared Spectrum: Authentic
• Molecular Formula: C8H10N4O2
• Beilstein: 26,461
• Specific Gravity: 1.23
• Solubility Information: Solubility in water: 20g/l (20°C). Other solubilities: 1g/66 mL alcohol,1g/50 mL acetone,freely soluble in pyrrole,soluble in ethyl acetate
• InChI Key: RYYVLZVUVIJVGH-UHFFFAOYSA-N
• SMILES: CN1C=NC2=C1C(=O)N(C)C(=O)N2C
• Molecular Weight (g/mol): 194.19
• ChEBI: CHEBI:27732
• Percent Purity: 98.5%
• Physical Form: Crystalline Powder or Crystals

• CAS: 58-08-2
• Color: White
• Loss on Drying: 0.5% max.
• Assay Percent Range: 0.1% max. (total impurities) (HPLC)
• MDL Number: MFCD00005758
• Merck Index: 15,1639
• Synonym: caffeine, 1,3,7-trimethylxanthine, guaranine, thein, cafeina, methyltheobromine, koffein, mateina, theine, alert-pep
• Sublimation Point: 178 °C
• Residual Solvents: meets the requirements
• IUPAC Name: 1,3,7-trimethylpurine-2,6-dione
• PubChem CID: 2519
• Formula Weight: 194.19
• Related Substances: 0.5% max. (TLC)
• Chemical Name or Material: Caffeine, 98.5%

Safety and Handling

GHS H Statement:
Harmful if swallowed.

GHS P Statement:
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
Wear protective gloves/eye protection/face protection.

WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.

GHS Signal Word: Warning

missing translation for 'einecsNumber' : 200-362-1

missing translation for 'rtecsNumber' : EV6475000

missing translation for 'tsca' : TSCA

Product Identifier

• Caffeine

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4

Hazard Statement

• H302-Harmful if swallowed.

Precautionary Statement

• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.

RUO – Research Use Only