Epredia™ Lab Vision™ Bcl-6 Ab-2, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry experiments with Epredia™ Bcl-6 Ab-2, Mouse Monoclonal Antibody.

Brand:  Epredia™ MS-1114-S

Product Code. 12689006

Description

Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas. Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin's lymphomas and Bcl-6 rearrangements have been detected in 33%-45% of diffuse large B cell lymphomas. Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt's lymphomas and in nodular, lymphocyte predominant Hodgkin's disease.

Host Species: Mouse

Clone: BL6.02, same as PG-B6p

Isotype: IgG1/κ

Species Reactivity: Human, Cow, Rabbit, Rat, Sheep and Pig. Others not tested.

Epitope: aa 3-484

Immunogen: Recombinant protein corresponding to amino acids 3-484 of the human Bcl-6 protein

Positive Control: Tonsil

Cellular Localization: Nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Bcl-6 Ab-2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Immunogen: Recombinant protein corresponding to amino acids 3-484 of the human Bcl-6 protein
• Quantity: 1 mL
• Research Discipline: Apoptosis
• Target Species: Bovine, Human, Porcine, Rabbit, Rat, Sheep
• Isotype: IgG2a κ

• Applications: Immunohistochemistry (Paraffin)
• Clone: BL6.02; same as PG-B6p
• Host Species: Mouse
• Purification Method: Tonsil
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated