WDR74 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA531322

Product Code. 13445837

Description

Recommended positive controls: NT2D1, IMR32, U87-MG. Predicted reactivity: Mouse (90%), Rat (91%), Pig (92%), Bovine (91%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The yeast nucleolar protein NOP7 is necessary for the maturation of 66S preribosomes and interacts with numerous other proteins. One such protein is an essential, conserved WD repeat protein, NOP seven-associated protein 1 (NSA1), that is also required for the yeast 66S ribosome assembly. NSA1 is also associated with the AAA ATPase Rix7, and release of NSA1 from a novel late nucleolar pre-60S requires the Rix7 function. NSA1 has also been found upregulated in mammalian cancer cells, suggesting it may also play a role in cell proliferation.

Specifications

• Antigen: WDR74
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WDR74
• Gene Alias: 5730436H21Rik; AA407588; NOP seven-associated protein 1; NSA1; WD repeat domain 74; WD repeat-containing protein 74; Wdr74
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54663
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q6RFH5
• Gene Symbols: WDR74
• Immunogen: Recombinant fragment corresponding to a region within amino acids 50 and 266 of Human WDR74
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG