SIN3B Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA530707

Product Code. 13445217

Description

Recommended positive controls: HepG2, HCT116, mouse brain. Predicted reactivity: Mouse (92%), Rat (91%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.

Specifications

• Antigen: SIN3B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SIN3B
• Gene Alias: 2810430C10Rik; Histone deacetylase complex subunit Sin3b; KIAA0700; Paired amphipathic helix protein Sin3b; SIN3 homolog B, transcription regulator; SIN3 homolog B, transcriptional regulator; SIN3 transcription regulator family member B; SIN3 transcription regulator homolog B; SIN3B; Transcriptional corepressor Sin3b; transcriptional regulator, SIN3 yeast homolog B; transcriptional regulator, SIN3B; transcriptional regulator, SIN3B (yeast)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20467, 23309
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
• Concentration: 0.57 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O75182, Q62141
• Gene Symbols: SIN3B
• Immunogen: Recombinant fragment corresponding to a region within amino acids 15 and 245 of Human SIN3B
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG