5-(Trifluoromethoxy)isatin, 98%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11457176	Thermo Scientific Alfa Aesar B25494.03	1 g
11467176	Thermo Scientific Alfa Aesar B25494.06	5 g

Description

5-(Trifluoromethoxy)isatin is used as a reactant for preparation of oxindole derivatives as TAk1 kinase inhibitors and of isatin thiosemicarbazones via condensation with thiosemicarbazones as herpes simplex virus (HSV) inhibitors. It is also used as a reactant for synthesis of 3-substituted 2-indolinone RET kinase inhibitors and for preparation of indolone acetamides as antiseizure agents.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
5-(Trifluoromethoxy)isatin is used as a reactant for preparation of oxindole derivatives as TAk1 kinase inhibitors and of isatin thiosemicarbazones via condensation with thiosemicarbazones as herpes simplex virus (HSV) inhibitors. It is also used as a reactant for synthesis of 3-substituted 2-indolinone RET kinase inhibitors and for preparation of indolone acetamides as antiseizure agents.

Solubility
Insoluble in water.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.

Chemical Identifiers

• CAS: 169037-23-4
• Molecular Weight (g/mol): 231.13
• InChI Key: XHAJMVPMNOBILF-UHFFFAOYSA-N
• PubChem CID: 2732752
• SMILES: C1=CC2=C(C=C1OC(F)(F)F)C(=O)C(=O)N2

• Molecular Formula: C9H4F3NO3
• MDL Number: MFCD00192524
• Synonym: 5-trifluoromethoxy isatin, 5-trifluoromethoxy indoline-2,3-dione, 5-trifluoromethoxy-1h-indole-2,3-dione, 5-trifluoromethoxyisatin, 1h-indole-2,3-dione, 5-trifluoromethoxy, 5-trifluoromethoxy-2,3-indolinedione, buttpark 34\07-90, acmc-209dz9, d0zr2t
• IUPAC Name: 5-(trifluoromethoxy)-1H-indole-2,3-dione

Specifications

• CAS: 169037-23-4
• Molecular Formula: C9H4F3NO3
• Synonym: 5-trifluoromethoxy isatin, 5-trifluoromethoxy indoline-2,3-dione, 5-trifluoromethoxy-1h-indole-2,3-dione, 5-trifluoromethoxyisatin, 1h-indole-2,3-dione, 5-trifluoromethoxy, 5-trifluoromethoxy-2,3-indolinedione, buttpark 34\07-90, acmc-209dz9, d0zr2t
• InChI Key: XHAJMVPMNOBILF-UHFFFAOYSA-N
• IUPAC Name: 5-(trifluoromethoxy)-1H-indole-2,3-dione
• PubChem CID: 2732752
• Percent Purity: 98%

• Melting Point: 170°C to 172°C
• MDL Number: MFCD00192524
• Solubility Information: Insoluble in water.
• SMILES: C1=CC2=C(C=C1OC(F)(F)F)C(=O)C(=O)N2
• Molecular Weight (g/mol): 231.13
• Formula Weight: 231.13
• Chemical Name or Material: 5-(Trifluoromethoxy)isatin

Safety and Handling

missing translation for 'tsca' : No

Recommended Storage : Ambient temperatures

RUO – Research Use Only