Phospho-FANCD2 (Ser330) Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 19543-1-AP-100UL

Product Code. 16889074

Description

The antibody is specific to phospho-Ser(330) of FANCD2.

Fanconi anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANCD2, targeting nuclear foci containing the BRCA1 protein.

Specifications

• Antigen: Phospho-FANCD2 (Ser330)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FANCD2
• Gene Alias: FA D2, FA4, FACD, FAD, FAD2, FANCD, FANCD2, Protein FACD2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2177
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.37 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9BXW9
• Gene Symbols: FANCD2
• Immunogen: Peptide
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG