p-Toluoyl chloride, 99%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11423067	Thermo Scientific Alfa Aesar A15581.22	100 g
11433067	Thermo Scientific Alfa Aesar A15581.36	500 g
11443067	Thermo Scientific Alfa Aesar A15581.0E	2500 g

Description

p-Toluoyl chloride was used to prepare antigen, Tolyl-amido-human serum albumin. It is used as a reagent to synthesize (+)-Yashabushitriol, derivatives of Desloratadine.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
p-Toluoyl chloride was used to prepare antigen, Tolyl-amido-human serum albumin. It is used as a reagent to synthesize (+)-Yashabushitriol, derivatives of Desloratadine.

Solubility
Reacts with water alcohol.

Notes
Store at room temperature. Incompatible with oxidizing agent, acids, bases, active metals, alcohols, amines.

Chemical Identifiers

• CAS: 874-60-2
• Molecular Weight (g/mol): 154.593
• InChI Key: NQUVCRCCRXRJCK-UHFFFAOYSA-N
• PubChem CID: 13405
• SMILES: CC1=CC=C(C=C1)C(=O)Cl

• Molecular Formula: C8H7ClO
• MDL Number: MFCD00000696
• Synonym: p-toluoyl chloride, benzoyl chloride, 4-methyl, p-methylbenzoyl chloride, 4-toluoyl chloride, p-toluyl chloride, p-toluic acid chloride, 4-methylbenzoic acid chloride, 4-methylbenzoylchloride, 4-methyl-benzoyl chloride, unii-092e36pwl4
• IUPAC Name: 4-methylbenzoyl chloride

Specifications

• CAS: 874-60-2
• Density: 1.169
• Flash Point: 82°C (179°F)
• Molecular Formula: C8H7ClO
• MDL Number: MFCD00000696
• Beilstein: 471492
• Synonym: p-toluoyl chloride, benzoyl chloride, 4-methyl, p-methylbenzoyl chloride, 4-toluoyl chloride, p-toluyl chloride, p-toluic acid chloride, 4-methylbenzoic acid chloride, 4-methylbenzoylchloride, 4-methyl-benzoyl chloride, unii-092e36pwl4
• InChI Key: NQUVCRCCRXRJCK-UHFFFAOYSA-N
• IUPAC Name: 4-methylbenzoyl chloride
• PubChem CID: 13405
• Percent Purity: 99%
• Chemical Name or Material: p-Toluoyl Chloride

• Melting Point: °C to 2°C
• Boiling Point: 225°C to 227°C
• Assay Percent Range: 99%
• Refractive Index: 1.553
• UN Number: UN3265
• Sensitivity: Moisture sensitive
• Solubility Information: Reacts with water alcohol.
• SMILES: CC1=CC=C(C=C1)C(=O)Cl
• Molecular Weight (g/mol): 154.593
• Formula Weight: 154.6
• Physical Form: Liquid

Safety and Handling

GHS H Statement
H314-H318-H227

P210-P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c

H227-H314

missing translation for 'dotInformation' : Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.

missing translation for 'einecsNumber' : 212-864-8

missing translation for 'rtecsNumber' : XV1660000

missing translation for 'tsca' : Yes

missing translation for 'storageNote' : Moisture sensitive

Recommended Storage : Ambient temperatures

Product Identifier

• p-Toluoyl chloride

Signal Word

• Danger

Hazard Category

• Serious eye damage/eye irritation Category 1
• Skin corrosion/irritation Category 1 B

Hazard Statement

• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : 4-methyl-Benzoyl chloride

RUO – Research Use Only