Iodomethane, 99%, stab. with copper, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11620222	Thermo Scientific Alfa Aesar A10559.18	50 g
11440980	Thermo Scientific Alfa Aesar A10559.30	250 g
11420980	Thermo Scientific Alfa Aesar A10559.0B	1000 g

Description

Iodomethane is a methylating agent used for alkylating carbon, oxygen, sulfur, nitrogen and phosphorus nucleophiles. For example, phenol reacts with methyl iodide to give anisole. In the Monsanto process, the insitu formed iodomethane reacts with carbon monoxide in the presence of a rhodium complex to give acetyl iodide, which on hydrolysis yields acetic acid. It reacts with magnesium to form the Grignard reagent, methylmagnesium iodide used in organic synthesis. It finds applications as an intermediate in the manufacture of pharmaceuticals and in phase transfer catalysts.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Iodomethane is a methylating agent used for alkylating carbon, oxygen, sulfur, nitrogen and phosphorus nucleophiles. For example, phenol reacts with methyl iodide to give anisole. In the Monsanto process, the insitu formed iodomethane reacts with carbon monoxide in the presence of a rhodium complex to give acetyl iodide, which on hydrolysis yields acetic acid. It reacts with magnesium to form the Grignard reagent, methylmagnesium iodide used in organic synthesis. It finds applications as an intermediate in the manufacture of pharmaceuticals and in phase transfer catalysts.

Solubility
Miscible with water.

Notes
Light and moisture sensitive. Store in cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, strong bases and oxygen.

Chemical Identifiers

• CAS: 74-88-4
• Molecular Weight (g/mol): 141.94
• InChI Key: INQOMBQAUSQDDS-UHFFFAOYSA-N
• PubChem CID: 6328
• IUPAC Name: iodomethane

• Molecular Formula: CH3I
• MDL Number: MFCD00001073
• Synonym: methyl iodide, monoiodomethane, methane, iodo, methyljodid, jod-methan, methyliodide, methyljodide, iodometano, joodmethaan, metylu jodek
• ChEBI: CHEBI:39282
• SMILES: CI

Specifications

• CAS: 74-88-4
• Density: 2.28
• Odor: Pungent
• Refractive Index: 1.53
• UN Number: UN2644
• Sensitivity: Light sensitive
• Synonym: methyl iodide, monoiodomethane, methane, iodo, methyljodid, jod-methan, methyliodide, methyljodide, iodometano, joodmethaan, metylu jodek
• InChI Key: INQOMBQAUSQDDS-UHFFFAOYSA-N
• IUPAC Name: iodomethane
• PubChem CID: 6328
• Formula Weight: 141.94
• Chemical Name or Material: Iodomethane, Stabilized with copper

• Melting Point: -67°C
• Boiling Point: 41°C to 43°C
• Molecular Formula: CH3I
• MDL Number: MFCD00001073
• Beilstein: 969135
• Merck Index: 14,6087
• Solubility Information: Miscible with water.
• SMILES: CI
• Molecular Weight (g/mol): 141.94
• ChEBI: CHEBI:39282
• Percent Purity: 99%

Safety and Handling

GHS H Statement
H301-H331-H351-H312-H315-H335
Toxic if swallowed.
Toxic if inhaled.
Suspected of causing cancer.
Harmful in contact with skin.
Causes skin irritation.
May cause respiratory irritation.

P201-P202-P260-P264b-P270-P271-P280i-P281-P301+P310-P302+P352-P304+P340-P305+P351+P338-P308+P313-P311-P312-P330-P332+P313-P362-P501c

H301+H331-H312-H315-H319-H335-H351

missing translation for 'dotInformation' : Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: METHYL IODIDE

missing translation for 'einecsNumber' : 200-819-5

missing translation for 'rtecsNumber' : PA9450000

missing translation for 'tsca' : Yes

Recommended Storage : Keep cold

Product Identifier

• Iodomethane

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3
• Acute toxicity Category 4
• Carcinogenicity Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H301-Toxic if swallowed.
• H312-Harmful in contact with skin.
• H315-Causes skin irritation.
• H331-Toxic if inhaled.
• H335-May cause respiratory irritation.
• H351-Suspected of causing cancer.

Precautionary Statement

• P201-Obtain special instructions before use.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P311-Call a POISON CENTER/doctor/ .

Supplemental information

• MIXTURE LIST-Contains : Methyl iodide

RUO – Research Use Only