EAPP Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16836714	Proteintech 16931-1-AP-20UL	20 μL
16826714	Proteintech 16931-1-AP-150UL	150 μL

Description

This protein may play an important role in the fine-tuning of both major E2F1 activities, the regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits p14(ARP) expression. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The C-terminal of EAPP binds the N-terminal of E2F1 and also interacts with E2F2 and E2F3, but not E2F4.

Specifications

• Antigen: EAPP
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Rat, Mouse
• Gene Accession No.: Q56P03, Q5BU09
• Gene ID (Entrez): 299043, 55837, 66266
• Immunogen: EAPP Fusion Protein Ag10403
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: EAPP

• Concentration: 0.17 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: BM036, C14orf11, E2F associated phosphoprotein, EAPP
• Gene Symbols: EAPP
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody