4'-Hydroxyacetophenone, 99%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11314719	Thermo Scientific Alfa Aesar A11974.22	100 g
11324719	Thermo Scientific Alfa Aesar A11974.36	500 g
11404004	Thermo Scientific Alfa Aesar A11974.0B	1000 g

Description

4?-Hydroxyacetophenone has been used as ketone component in the preparation of 1-aryl-3-phenethylamino-1-propanone hydrochlorides, potential cytotoxic agents, via Mannich reactions.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4′-Hydroxyacetophenone has been used as ketone component in the preparation of 1-aryl-3-phenethylamino-1-propanone hydrochlorides, potential cytotoxic agents, via Mannich reactions.

Solubility
Soluble in 95% Ethanol. Slightly soluble in water.

Notes
Store at room temperature. Keep away from oxidizing agents.

Chemical Identifiers

• CAS: 99-93-4
• Molecular Weight (g/mol): 136.15
• InChI Key: TXFPEBPIARQUIG-UHFFFAOYSA-N
• PubChem CID: 7469
• IUPAC Name: 1-(4-hydroxyphenyl)ethanone

• Molecular Formula: C8H8O2
• MDL Number: MFCD00002359
• Synonym: 4'-hydroxyacetophenone, 4-hydroxyacetophenone, 1-4-hydroxyphenyl ethanone, 4-acetylphenol, p-hydroxyacetophenone, piceol, ethanone, 1-4-hydroxyphenyl, p-acetylphenol, para-hydroxyacetophenone, p-oxyacetophenone
• ChEBI: CHEBI:28032
• SMILES: CC(=O)C1=CC=C(O)C=C1

Specifications

• CAS: 99-93-4
• Boiling Point: 286°C
• Molecular Formula: C8H8O2
• Beilstein: 774355
• Solubility Information: Soluble in 95% Ethanol. Slightly soluble in water.
• SMILES: CC(=O)C1=CC=C(O)C=C1
• Molecular Weight (g/mol): 136.15
• ChEBI: CHEBI:28032
• Percent Purity: 99%

• Melting Point: 106°C to 108°C
• Flash Point: 166°C (330°F)
• MDL Number: MFCD00002359
• Synonym: 4'-hydroxyacetophenone, 4-hydroxyacetophenone, 1-4-hydroxyphenyl ethanone, 4-acetylphenol, p-hydroxyacetophenone, piceol, ethanone, 1-4-hydroxyphenyl, p-acetylphenol, para-hydroxyacetophenone, p-oxyacetophenone
• InChI Key: TXFPEBPIARQUIG-UHFFFAOYSA-N
• IUPAC Name: 1-(4-hydroxyphenyl)ethanone
• PubChem CID: 7469
• Formula Weight: 136.15
• Chemical Name or Material: 4'-Hydroxyacetophenone

Safety and Handling

GHS H Statement
H301-H315-H319-H335
Toxic if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c

H302-H315-H319-H335

missing translation for 'einecsNumber' : 202-802-8

missing translation for 'rtecsNumber' : AM8750000

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

Product Identifier

• 4'-Hydroxyacetophenone

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H302-Harmful if swallowed.
• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.

Precautionary Statement

• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Supplemental information

• MIXTURE LIST-Contains : p-Hydroxyacetophenone

RUO – Research Use Only