Triisopropylsilane, 98%, Thermo Scientific Chemicals

Description

Triisopropylsilane is used as a protecting group in peptide synthesis and is also used as a reducing agent for the selective reduction of anomeric C-phenyl ketals. It is used in the selective silylation of primary hydroxyl groups without affecting the secondary hydroxyl group. It is used in the preparation of anti-1,2-diols catalyzed by a Ni(O) N-heterocyclic carbine complex with high diastereoselectivity.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Triisopropylsilane is used as a protecting group in peptide synthesis and is also used as a reducing agent for the selective reduction of anomeric C-phenyl ketals. It is used in the selective silylation of primary hydroxyl groups without affecting the secondary hydroxyl group. It is used in the preparation of anti-1,2-diols catalyzed by a Ni(O) N-heterocyclic carbine complex with high diastereoselectivity.

Solubility
Immiscible with water.

Notes
Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong acids and strong oxidizing agents.

Specifications

• Boiling Point: 166°C
• Quantity: 5 g
• Linear Formula: [(CH₃)₂CH]₃SiH
• UN Number: UN1993
• Beilstein: 1733718
• Flash Point: 35°C (95°F)
• Solubility Information: Immiscible with water.
• IUPAC Name: tris(propan-2-yl)silane
• Formula Weight: 158.36
• Percent Purity: 98%
• Odor: Mild
• Refractive Index: 1.434
• Density: 0.773
• Chemical Name or Material: Triisopropylsilane

RUO – Research Use Only