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Invitrogen™ Oregon Green™ 488 BAPTA-1 dextran, Potassium Salt, 10,000 MW, Anionic

Dextran forms of these calcium indicators show dramatic reduction in both leakage and compartmentalization compared to AM ester forms

Brand:  Invitrogen™ O6798

334.68 GBP valid until 2024-03-29
Use promo code "21615" to get your promotional price.



Code : 50

Additional Details : Weight : 0.00525kg

Product Code. 11579186

  • £502.00 / 5mg
Estimated Shipment: 16-04-2024
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For Research Use Only. All usage must comply with product instructions.
 

Description

Description

Labeled calcium indicators are molecules that exhibit increase in fluorescence upon binding Ca2+. They have uses in many calcium signaling investigations, including measuring intracellular Ca2+, following Ca2+ influx and release, and multiphoton excitation imaging of Ca2+ in living tissues.

  • Cells may be physically loaded with cell-impermeant salt forms of these dextran-conjugated indicators using patch pipet or microinjection
  • Fluorescence signal from these cells is measured using fluorescence microscopy
  • Label (Ex/Em): Oregon Green 488 BAPTA-1 (494/523nm)
  • Fluorescence intensity increase upon binding Ca2+: approximately 14 fold
  • Exhibit fluorescence increase upon binding Ca2+ with little shift in wavelength
  • These probes are excited by visible light, and because energy required for excitation is low, potential for cellular photodamage is reduced
  • Commonly used laser-based instruments (i.e., confocal laser scanning microscopes) are able to efficiently excite these indicators, and their emissions are in regions of spectrum where cellular autofluorescence and scattering backgrounds are often less of problem

Calcium Detection, Cell Analysis, Cell Viability, Proliferation and Function, Ionic Homeostasis and Signaling

Order Info

Shipping Condition: Room temperature

Specifications

Specifications

Store in freezer -5°C to -30°C and protect from light.
Potassium Assay
Reagent
Oregon Green™
Fluorescent
Fluorescence Microscope, Flow Cytometer, Microplate Reader
Fluorescent Dye-Based
Room Temperature
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For Research Use Only. Not for use in diagnostic procedures.