Epiandrosterone, 99%, Thermo Scientific Chemicals

Description

Epiandrosterone, 99%, CAS# 481-29-8, is a steroid hormone with weak androgenic activity. It is a metabolite and a precursor of testosterone and estradiol with hypolipidemic and anabolic activities.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Epiandrosterone is a steroid hormone, derived from 5 α-androstane

• It is a dehydroepiandrosterone metabolite and an androgen

• It is a precursor of testosterone and estradiol with hypolipidemic and anabolic activities

Applications

• Epiandrosterone presents some neurological activity since it can bind to the ɣ-aminobutyric acid (GABA)/benzodiazepine-receptor complex (GABA-RC), acting as a negative non-competitive modulator of GABA-RC, and signaling through the N-methyl-D-aspartate receptor

• It can also inhibit the pentose phosphate pathway, dilating blood vessels pre-contracted by partial depolarization

• Epiandrosterone can inhibit the thromboxane A2 synthesis in activated platelets, decrease plasma plasminogen activator inhibitor type 1, reduce tissue plasminogen activator antigen, improve insulin-like growth factor 1 serum levels, and increase the synthesis of cyclic guanosine monophosphate and nitric oxide

• In vitro assays demonstrate that this compound inhibits Junin virus replication vitro anti-adenovirus (AdV) activity

• Epiandrosterone affects glucose oxidation and interleukin-1 beta in in vitro pancreatic islets

Specifications

• CAS: 481-29-8
• Melting Point: 171°C to 177°C
• Color: White
• Loss on Drying: 0.5% max.
• Infrared Spectrum: Authentic
• Assay Percent Range: 99%
• Packaging: Glass bottle
• Molecular Formula: C19H30O2
• MDL Number: MFCD00064134
• Quantity: 5 g
• Specific Rotation Condition: +91° (20°C c=1,CH₃OH)
• Specific Rotation: +88° to +94° (20°C, 589nm) (c=1, CH3OH)
• Synonym: epiandrosterone, trans-androsterone, isoandrosterone, 3beta-hydroxy-5alpha-androstan-17-one, 3beta-hydroxyetioallocholan-17-one, epi-andosterone, 5alpha-androstan-3beta-ol-17-one, iso-androsterone, d-epiandrosterone, 3-epiandrosterone
• InChI Key: QGXBDMJGAMFCBF-LUJOEAJASA-N
• SMILES: CC12CCC(CC1CCC3C2CCC4(C3CCC4=O)C)O
• IUPAC Name: (3S,5S,8R,9S,10S,13S,14S)-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one
• Molecular Weight (g/mol): 290.447
• PubChem CID: 441302
• ChEBI: CHEBI:541975
• Formula Weight: 290.44
• Percent Purity: ≥98.5%
• Physical Form: Crystalline Powder
• Chemical Name or Material: Epiandrosterone, 99%

RUO – Research Use Only