TCR V beta F1 Monoclonal Antibody (8A3), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen TCR1151

Product Code. 11898821

Description

TCR1151 targets TCR Beta F1 in FACS, FISH, IHC, IHC(P), IP, and WB applications and shows reactivity with Human samples. The TCR1151 immunogen is human TCR β chain constant region. TCR1151 detects TCR Beta F1 which has a predicted molecular weight of approximately 13 kDa.

The T Cell Receptor alpha beta (TCRab) is a heterodimeric membrane receptor that consists of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 proteins. TCRab participates in the activation of T-cells in response to an antigen presented in the context of MHC. Engagement of the TCRab initiates signaling cascades that μgtimately result in cellular proliferation, differentiation, cytokine production, and/or activation-induced cell death. These signaling cascades regulate T-cell development, homeostasis, activation, acquisition of effector functions and apoptosis. Cells expressing TCRab constitute the vast majority of T cells in both human and mouse.

Specifications

• Antigen: TCR V beta F1
• Classification: Monoclonal
• Concentration: 0.15 mg/mL
• Formulation: PBS with 0.5% BSA and 0.1% sodium azide
• Gene Accession No.: 0
• Gene Symbols: TRB
• Immunogen: Human TCR ß chain constant region
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: 8A3
• Conjugate: Unconjugated
• Gene: TRB
• Gene Alias: T cell receptor beta locus; tcr beta f1; TCRB; TRB; TRB@
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 6957
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

Product Identifier

• Pierce Purified Antibody(ies)

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4

Hazard Statement

• H302-Harmful if swallowed.

Precautionary Statement

• P264-Wash hands thoroughly after handling.
• P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information

• MIXTURE LIST-Contains : sodium azide